Correction: Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus.

نویسندگان

  • Chantal E Hargreaves
  • Chisako Iriyama
  • Matthew J J Rose-Zerilli
  • Sietse Q Nagelkerke
  • Khiyam Hussain
  • Rosalind Ganderton
  • Charlotte Lee
  • Lee R Machado
  • Edward J Hollox
  • Helen Parker
  • Kate V Latham
  • Taco W Kuijpers
  • Kathleen N Potter
  • Sarah E Coupland
  • Andrew Davies
  • Michael Stackpole
  • Melanie Oates
  • Andrew R Pettitt
  • Martin J Glennie
  • Mark S Cragg
  • Jonathan C Strefford
چکیده

Fig 4 is incorrect. The figure is an older version, which contains an inaccurate summary of data. The authors have provided a corrected version here. Copyright: © 2016 Hargreaves et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus

Cancer immunotherapy has been revolutionised by the use monoclonal antibodies (mAb) that function through their interaction with Fc gamma receptors (FcγRs). The low-affinity FcγR genes are highly homologous, map to a complex locus at 1p23 and harbour single nucleotide polymorphisms (SNPs) and copy number variation (CNV) that can impact on receptor function and response to therapeutic mAbs. This...

متن کامل

Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field

BACKGROUND There is now intense interest in the role of HIV-specific antibodies and the engagement of FcγR functions in the control and prevention of HIV infection. The analyses of the RV144 vaccine trial, natural progression cohorts, and macaque models all point to a role for Fc-dependent effector functions, such as cytotoxicity (ADCC) or phagocytosis (ADCP), in the control of HIV. However, re...

متن کامل

Association of FCγRIIA (CD32) polymorphism with susceptibility to brucellosis

Background: Brucellosis is the major bacterial zoonoses of global importance caused by Brucella spps. FCγRIIA receptor plays a central role in phagocytosis of IgG2-opsonized bacteria. FCγRIIA exhibits allelic polymorphisms with different capacities for binding IgG2 and phagocytosis. Cells expressing Fc γ RIIa-H131, bind more efficiently to complexes of IgG2 than those expressi...

متن کامل

تهیه سازه‌های مناسب به‌منظور بیان ژن اینترفرون گامای انسانی در Leishmania tarentolae

 Background and Objective: The aim of the present study was to express recombinant human interferon-gamma in Leishmania tarentolae. The Leishmania expression system represents the combination of easy handling known from bacterial expression systems with the potential of a eukaryotic protein expression, folding and modification system. The trypanosomatid protozoan host Leishmania tarent...

متن کامل

Genetic Polymorphism of the Melatonin Receptor 1A Locus in Iranian Shall and Karakul Sheep

The genotypes of the melatonin receptor 1A (MTNR1A) were determined by PCR-RFLP in the native Iranian Shall  and karakul breeds of sheep . Blood samples were collected from 60 karakul and 50 Shall breeds. Genomic DNA was extracted based on the Guanidin Thiocyanate-slica gel method. After PCR reaction, PCR products were digested by the Mnl1 restriction enzyme. The MTNR1A locus had two genotypes ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • PloS one

دوره 11 3  شماره 

صفحات  -

تاریخ انتشار 2016